Young Anthony March, living in London, inherits a considerable amount of money, but his crooked uncle Dr. Manuel Ceneri steals it. When Anthony gets suspicious, Ceneri's partner in crime, Macari, persuades Ceneri to kill him. However, just as they commit the murder a blind man, Gilbert Vaughan, mistakenly enters the house. Anthony's sister Pauline sees the murder, faints and loses her memory. Thinking they have gotten away with the murder, Ceneri and Macari soon find out that they're in for a shock.
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